Preparations and Applications of Polyethyleneimine-Immobilized Cellulose Fibers for Endotoxin Removal
نویسندگان
چکیده
منابع مشابه
Methods of endotoxin removal from biological preparations: a review.
PURPOSE Endotoxins, also called lipopolysaccharides (LPS), are major contaminants found in commercially available proteins or biologically active substances, which often complicate study of the biological effects of the main ingredient. The presence of small amounts of endotoxin in recombinant protein preparations can cause side effects in host organism such as endotoxin shock, tissue injury, a...
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A modified microfiltration membrane has been prepared by blending a matrix polymer with a functional polymer. Cellulose acetate (CA) was blended with polyethyleneimine (PEI), which was then crosslinked by polyisocyanate, in a mixture of solvents. In the membrane, PEI can supply coupling sites for ligands in affinity separation or be used as ligands for metal chelating, removal of endotoxin or i...
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Severe sepsis results in high morbidity and mortality. Immunomodulation strategies could be an adjunctive therapy to treat sepsis. Endotoxin is a component of gram-negative bacteria and plays an important role in the pathogenesis of septic shock when it is recognized by immune cells. Removal of endotoxin could be an effective adjunctive approach to the management of sepsis. Devices to adsorb en...
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A novel work was performed for fabrication and modification of composite nanofiltration (NF) membrane by polymerization reaction between polyethyleneimine (PEI) and triphthaloyldechloride (TPC). the main purpose of this work was water treatment. polysulfone was applied as a main polymer of substrate. The result of reaction between PEI and TPC would be formation of polyamide layer on the membran...
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ژورنال
عنوان ژورنال: Polymer Journal
سال: 1995
ISSN: 0032-3896,1349-0540
DOI: 10.1295/polymj.27.831